HM13

Across TCGA patient cohorts, HM13 mutation is significantly associated with the immune_cell of many other genes, with 5 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible HM13-associated genes across cancer lineages are Th2 cells, GMP, and lymphatic Endothelial cells. Each is linked with HM13 in more than 3 cancer types. Because this analysis shows association rather than direction, both HM13-to-partner and partner-to-HM13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Th2 cells grouped by HM13-low versus HM13-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HM13→partner) and Y-score (partner→HM13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Th2 cells →	+0.179	+1.736	.003	.007	3	4
STAD	GMP →	+0.104	+3.169	.005	.049	3	1
UCEC	lymphatic Endothelial cells →	-0.020	-2.374	.015	.003	3	1
SKCM	HSC →	-0.095	-3.290	.026	.010	2	1
UCEC	Plasma cells →	-0.018	-2.346	.014	.021	2	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Th2 cells by HM13 expression — UCEC

Explore this box plot interactively →