HM13

Across TCGA cell cohorts, HM13 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,951 significant associations in total. BONE shows the largest number of these associations.

The most reproducible HM13-associated GO terms across cancer lineages are Protein folding, Response to unfolded protein, and Protein localization to endoplasmic reticulum. Each is linked with HM13 in more than 12 cancer types. Because this analysis shows association rather than direction, both HM13-to-partner and partner-to-HM13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein folding grouped by HM13-low versus HM13-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HM13→partner) and Y-score (partner→HM13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Protein folding →	+0.052	+0.469	<.001	<.001	3	13
OVARY	Response to unfolded protein →	+0.085	+1.114	<.001	<.001	3	13
URINARY_TRACT	Protein localization to endoplasmic reticulum →	+0.091	+0.613	<.001	.002	3	13
BONE	Cellular response to unfolded protein →	+0.111	+0.829	.003	.005	3	13
STOMACH	Response to topologically incorrect protein →	+0.096	+0.789	.001	<.001	3	13
BONE	Negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway →	+0.226	+0.730	.001	.005	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,951 associations by consensus.

Protein folding by HM13 expression — BLOOD_Leukemia

Explore this box plot interactively →