HM13-AS1

Across TCGA pan-cancer cohorts, HM13-AS1 RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated HM13-AS1 data layer.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher HM13-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated HM13-AS1 expression acts as an unfavorable survival marker, although some lineages such as UCS and DLBC show a favorable association.

COAD, LGG, and ACC are the cancer types where HM13-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	OS	Tertile	All	0.727	0.867	.007	30	view →
LGG	DFS	Tertile	All	0.642	0.810	<.001	22	view →
ACC	DFS	Median	All	0.561	0.892	.001	21	view →
UVM	OS	Median	III,IV	0.417	0.828	.018	19	view →
KIRC	DFS	Tertile	All	0.803	0.894	.010	16	view →
KIRP	DFS	Quartile	IV	0.162	0.476	.017	12	view →
UCS	DFS	Quartile	III,IV	0.560	0.160	.038	12	view →
THCA	OS	Quartile	All	0.768	1.000	.010	12	view →
DLBC	DFS	Median	IV	0.860	0.306	.021	10	view →
LIHC	DFS	Tertile	All	0.185	0.453	.008	10	view →
UCEC	DFS	Tertile	All	0.869	0.934	.027	10	view →
PAAD	DFS	Quartile	All	0.399	0.118	.010	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

HM13-AS1–COAD (OS)

Open the COAD breakdown →