HLA-V

Across TCGA pan-cancer cohorts, HLA-V Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated HLA-V data layer compared with 20 for mass-spec protein.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher HLA-V Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated HLA-V expression acts as an unfavorable survival marker.

COAD are the cancer types where HLA-V Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	OS	Median	All	0.113	0.806	<.001	7	view →

Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

HLA-V–COAD (OS)

Open the COAD breakdown →