HLA-T

Across TCGA patient cohorts, HLA-T RNA expression is significantly associated with the go_rna of many other GO terms, with 6,965 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible HLA-T-associated GO terms across cancer lineages are Autophagosome maturation, Lysosomal transport, and Cytosolic transport. Each is linked with HLA-T in more than 27 cancer types. Because this analysis shows association rather than direction, both HLA-T-to-partner and partner-to-HLA-T results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Autophagosome maturation grouped by HLA-T-low versus HLA-T-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HLA-T→partner) and Y-score (partner→HLA-T) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Autophagosome maturation →	+0.075	+0.519	<.001	<.001	3	28
ESCA	Lysosomal transport →	+0.066	+0.429	.001	<.001	3	28
ESCA	Cytosolic transport →	+0.047	+0.359	.002	<.001	3	27
ESCA	Golgi vesicle transport →	+0.073	+0.377	.001	<.001	3	27
ESCA	Obsolete selective autophagy →	+0.073	+0.376	<.001	<.001	3	27
ESCA	Vacuolar transport →	+0.069	+0.417	<.001	<.001	3	27

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,965 associations by consensus.

Autophagosome maturation by HLA-T expression — ESCA

Explore this box plot interactively →