HLA-DRA

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, HLA-DRA RNA expression is significantly associated with the protein abundance of many other proteins, with 22,515 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible HLA-DRA-associated proteins across cancer lineages are ARHGAP15, ARHGAP45, and PLCB2. Each is linked with HLA-DRA in more than 9 cancer types. Because this analysis shows association rather than direction, both HLA-DRA-to-partner and partner-to-HLA-DRA results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HLA-DRA→partner) and Y-score (partner→HLA-DRA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMARHGAP15 →+0.706+1.385<.001<.001310
GBMARHGAP45 →+0.658+1.243<.001<.001310
GBMPLCB2 →+0.666+1.396<.001<.001310
UCECIL4I1 →+0.724+1.312.001.001310
LSCCANKRD44 →+0.524+1.189<.001<.001310
HNSCLAP3 →+0.852+1.899<.001<.001310
Each partner links to its Q-omics profile. Showing the 6 strongest of 22,515 associations by consensus.

Exploration