HLA-DPB2

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, HLA-DPB2 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,385 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible HLA-DPB2-associated proteins across cancer lineages are HLA-DRA, SAMHD1, and APOL3. Each is linked with HLA-DPB2 in more than 8 cancer types. Because this analysis shows association rather than direction, both HLA-DPB2-to-partner and partner-to-HLA-DPB2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HLA-DPB2→partner) and Y-score (partner→HLA-DPB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVHLA-DRA →+1.116+0.861<.001<.00139
HNSCSAMHD1 →+0.535+0.554<.001<.00139
UCECAPOL3 →+0.759+0.542<.001.00238
UCECARHGAP45 →+0.546+0.639<.001<.00138
HNSCDOCK10 →+0.473+0.427<.001<.00138
GBMDOCK2 →+0.515+0.525<.001<.00138
Each partner links to its Q-omics profile. Showing the 6 strongest of 11,385 associations by consensus.

Exploration