HKDC1

Across TCGA patient cohorts, HKDC1 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,322 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible HKDC1-associated proteins across cancer lineages are PARP4, RUFY1, and IL18. Each is linked with HKDC1 in more than 4 cancer types. Because this analysis shows association rather than direction, both HKDC1-to-partner and partner-to-HKDC1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HKDC1 versus PARP4 in GBM, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HKDC1→partner) and Y-score (partner→HKDC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PARP4 →	+0.476	+0.933	.001	<.001	3	5
LSCC	RUFY1 →	+0.251	+0.850	<.001	<.001	3	4
HNSC	IL18 →	+0.581	+0.902	.008	.002	3	4
LSCC	LRRFIP1 →	+0.253	+0.829	<.001	<.001	3	4
GBM	ANXA4 →	+0.663	+0.845	<.001	<.001	3	4
CCRCC	PARP4_T101 →	+0.604	+1.258	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,322 associations by consensus.

HKDC1 vs PARP4 — GBM

Explore this scatter interactively →