HK2

Across TCGA patient cohorts, HK2 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,992 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible HK2-associated proteins across cancer lineages are ERO1A, KDM3A, and P4HA2. Each is linked with HK2 in more than 6 cancer types. Because this analysis shows association rather than direction, both HK2-to-partner and partner-to-HK2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HK2 versus ERO1A in GBM, with a Pearson correlation of 0.60.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HK2→partner) and Y-score (partner→HK2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ERO1A →	+0.596	+0.939	<.001	<.001	3	7
OV	KDM3A →	+0.447	+0.890	<.001	<.001	3	6
GBM	P4HA2 →	+0.799	+1.054	<.001	<.001	3	6
PDAC	TPI1_S80 →	+0.534	+0.811	.002	<.001	2	7
PDAC	SCLY →	-0.353	-0.711	<.001	<.001	3	6
LSCC	SLC2A1 →	+0.773	+0.718	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,992 associations by consensus.

HK2 vs ERO1A — GBM

Explore this scatter interactively →