HK2

Across TCGA patient cohorts, HK2 protein abundance is significantly associated with the RNA expression of many other genes, with 18,808 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible HK2-associated genes across cancer lineages are SLC2A1, GAPDH, and TNXB. Each is linked with HK2 in more than 8 cancer types. Because this analysis shows association rather than direction, both HK2-to-partner and partner-to-HK2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HK2 versus SLC2A1 in LUAD, with a Pearson correlation of 0.62.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HK2→partner) and Y-score (partner→HK2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	SLC2A1 →	+1.305	+0.562	<.001	<.001	3	9
OV	GAPDH →	+0.928	+0.589	<.001	<.001	3	8
UCEC	TNXB →	-0.953	-0.385	.002	.002	3	8
CCRCC	CCL14 →	-0.577	-0.601	<.001	<.001	3	8
LSCC	FAM162A →	+0.915	+0.513	<.001	<.001	3	8
CCRCC	EMCN →	-1.085	-0.652	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,808 associations by consensus.

HK2 vs SLC2A1 — LUAD

Explore this scatter interactively →