HJURP

Across TCGA patient cohorts, HJURP protein abundance is significantly associated with the RNA expression of many other genes, with 5,739 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible HJURP-associated genes across cancer lineages are TIMELESS, KIF2C, and EME1. Each is linked with HJURP in more than 2 cancer types. Because this analysis shows association rather than direction, both HJURP-to-partner and partner-to-HJURP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HJURP versus TIMELESS in OV, with a Pearson correlation of 0.57.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HJURP→partner) and Y-score (partner→HJURP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	TIMELESS →	+1.449	+1.168	<.001	.009	3	3
PDAC	KIF2C →	+1.545	+0.826	<.001	.005	3	3
OV	EME1 →	+1.304	+1.114	<.001	.002	3	3
PDAC	MCM10 →	+1.474	+1.142	.008	.004	3	3
PDAC	TRIP13 →	+1.302	+0.863	.004	.004	3	3
UCEC	CKAP2L →	+1.205	+0.962	.009	.009	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,739 associations by consensus.

HJURP vs TIMELESS — OV

Explore this scatter interactively →