HJURP

Across TCGA cell cohorts, HJURP RNA expression is significantly associated with the go_rna of many other GO terms, with 4,622 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible HJURP-associated GO terms across cancer lineages are Meiotic cell cycle, Nuclear division, and Regulation of mitotic sister chromatid separation. Each is linked with HJURP in more than 19 cancer types. Because this analysis shows association rather than direction, both HJURP-to-partner and partner-to-HJURP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Meiotic cell cycle grouped by HJURP-low versus HJURP-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HJURP→partner) and Y-score (partner→HJURP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Meiotic cell cycle →	+0.100	+1.351	<.001	<.001	3	20
OESOPHAGUS	Nuclear division →	+0.103	+1.336	.009	<.001	3	20
OESOPHAGUS	Regulation of mitotic sister chromatid separation →	+0.177	+0.880	<.001	.006	3	19
SOFT_TISSUE	Nuclear chromosome segregation →	+0.129	+1.573	<.001	<.001	3	19
STOMACH	Regulation of chromosome separation →	+0.163	+1.379	<.001	<.001	3	19
BLOOD_Myeloma	Chromosome segregation →	+0.111	+1.365	.002	.001	3	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,622 associations by consensus.

Meiotic cell cycle by HJURP expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →