HIVEP3

Across TCGA patient cohorts, HIVEP3 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,448 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible HIVEP3-associated proteins across cancer lineages are HIVEP3_S1964, DOCK11, and HIVEP3_S720. Each is linked with HIVEP3 in more than 6 cancer types. Because this analysis shows association rather than direction, both HIVEP3-to-partner and partner-to-HIVEP3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HIVEP3 versus HIVEP3_S1964 in GBM, with a Pearson correlation of 0.62.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HIVEP3→partner) and Y-score (partner→HIVEP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	HIVEP3_S1964 →	+0.871	+1.181	<.001	<.001	3	7
OV	DOCK11 →	+0.627	+0.509	<.001	.002	3	6
HNSC	HIVEP3_S720 →	+0.644	+1.269	.002	<.001	2	7
LSCC	HIVEP3_S948 →	+0.732	+0.715	<.001	<.001	3	6
LSCC	DAP3 →	-0.402	-0.682	<.001	.002	3	5
BRCA	MACF1 →	+0.308	+0.700	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,448 associations by consensus.

HIVEP3 vs HIVEP3_S1964 — GBM

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