HIVEP3

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, HIVEP3 protein abundance is significantly associated with the RNA expression of many other genes, with 5,539 significant associations in total. GBM shows the largest number of these associations.

The most reproducible HIVEP3-associated genes across cancer lineages are DBI, CHRNA5, and GAN. Each is linked with HIVEP3 in more than 2 cancer types. Because this analysis shows association rather than direction, both HIVEP3-to-partner and partner-to-HIVEP3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HIVEP3 versus DBI in BRCA, with a Pearson correlation of -0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HIVEP3→partner) and Y-score (partner→HIVEP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCADBI →-1.151-0.718<.001<.00133
LSCCCHRNA5 →-0.963-0.573.001.00233
BRCAGAN →-0.684-0.737<.001<.00133
GBMNSF →-0.518-0.484<.001.00133
LSCCTBL1X →-0.919-0.661.001<.00132
BRCAGATA3 →+3.160+0.748<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 5,539 associations by consensus.

HIVEP3 vs DBI — BRCA

Per-sample scatter of HIVEP3 vs DBI in BRCA (Pearson r = -0.40).

Explore this scatter interactively →

Exploration