HIVEP2

Across TCGA patient cohorts, HIVEP2 protein abundance is significantly associated with the RNA expression of many other genes, with 6,450 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible HIVEP2-associated genes across cancer lineages are PAIP2, ANGPTL4, and FAM20A. Each is linked with HIVEP2 in more than 2 cancer types. Because this analysis shows association rather than direction, both HIVEP2-to-partner and partner-to-HIVEP2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HIVEP2 versus PAIP2 in CCRCC, with a Pearson correlation of -0.47.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HIVEP2→partner) and Y-score (partner→HIVEP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	PAIP2 →	-0.505	-0.706	<.001	<.001	3	3
PDAC	ANGPTL4 →	+1.709	+0.374	<.001	.002	3	3
BRCA	FAM20A →	+0.885	+0.414	<.001	<.001	3	2
BRCA	ELP2 →	-0.924	-0.292	<.001	.001	3	2
BRCA	PSAT1 →	+1.898	+0.289	<.001	.001	3	2
BRCA	P2RX4 →	-0.621	-0.358	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,450 associations by consensus.

HIVEP2 vs PAIP2 — CCRCC

Explore this scatter interactively →