HIVEP2

Across TCGA patient cohorts, HIVEP2 mutation is significantly associated with the total protein of many other genes, with 73 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible HIVEP2-associated genes across cancer lineages are GAPDH, Cyclin-B1, and PAI-1. Each is linked with HIVEP2 in more than 3 cancer types. Because this analysis shows association rather than direction, both HIVEP2-to-partner and partner-to-HIVEP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GAPDH grouped by HIVEP2-low versus HIVEP2-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HIVEP2→partner) and Y-score (partner→HIVEP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	GAPDH →	+0.746	+3.000	.013	.035	3	4
CESC	Cyclin-B1 →	+0.474	+3.035	.005	.014	3	4
LUAD	PAI-1 →	+0.649	+2.115	.022	.018	3	3
CESC	IGFBP2 →	-0.545	-3.321	.048	.009	3	3
LUSC	ERK2 →	-0.273	-2.312	.040	.035	3	3
COAD	eEF2 →	+0.253	+1.708	.025	.026	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 73 associations by consensus.

GAPDH by HIVEP2 expression — LUSC

Explore this box plot interactively →