HIVEP2

Across TCGA cell cohorts, HIVEP2 mutation is significantly associated with the RNA expression of many other genes, with 1,016 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible HIVEP2-associated genes across cancer lineages are CCDC172, NPHS2, and C12orf57. Each is linked with HIVEP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both HIVEP2-to-partner and partner-to-HIVEP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CCDC172 grouped by HIVEP2-low versus HIVEP2-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HIVEP2→partner) and Y-score (partner→HIVEP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	CCDC172 →	+0.044	+4.369	<.001	.008	3	2
LUNG_SCLC	NPHS2 →	+0.021	+3.817	<.001	.004	3	2
BLOOD_Leukemia	C12orf57 →	+1.091	+3.351	.002	.003	3	2
LARGE_INTESTINE	TTC33 →	+0.605	+2.265	.001	.001	3	2
LARGE_INTESTINE	NR2C1 →	+0.520	+3.700	<.001	<.001	3	2
LARGE_INTESTINE	RSL24D1 →	+0.514	+2.389	.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,016 associations by consensus.

CCDC172 by HIVEP2 expression — SOFT_TISSUE

Explore this box plot interactively →