HIRIP3

Across TCGA patient cohorts, HIRIP3 protein abundance is significantly associated with the RNA expression of many other genes, with 15,849 significant associations in total. GBM shows the largest number of these associations.

The most reproducible HIRIP3-associated genes across cancer lineages are POLA1, RMI2, and PRIM1. Each is linked with HIRIP3 in more than 6 cancer types. Because this analysis shows association rather than direction, both HIRIP3-to-partner and partner-to-HIRIP3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HIRIP3 versus POLA1 in LSCC, with a Pearson correlation of 0.46.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HIRIP3→partner) and Y-score (partner→HIRIP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	POLA1 →	+0.667	+0.397	<.001	.002	3	7
BRCA	RMI2 →	+0.842	+0.455	<.001	<.001	3	7
HNSC	PRIM1 →	+0.713	+0.371	<.001	<.001	3	7
BRCA	KIF22 →	+1.082	+0.585	<.001	<.001	3	7
HNSC	ZNF174 →	+0.593	+0.367	<.001	<.001	3	6
BRCA	MAZ →	+0.913	+0.479	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,849 associations by consensus.

HIRIP3 vs POLA1 — LSCC

Explore this scatter interactively →