HIRIP3

Across TCGA cell cohorts, HIRIP3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,423 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible HIRIP3-associated GO terms across cancer lineages are Mitotic DNA replication, Interstrand cross-link repair, and Regulation of cell cycle checkpoint. Each is linked with HIRIP3 in more than 15 cancer types. Because this analysis shows association rather than direction, both HIRIP3-to-partner and partner-to-HIRIP3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitotic DNA replication grouped by HIRIP3-low versus HIRIP3-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HIRIP3→partner) and Y-score (partner→HIRIP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Mitotic DNA replication →	+0.191	+1.351	<.001	<.001	3	16
BLOOD_Myeloma	Interstrand cross-link repair →	+0.079	+0.718	<.001	<.001	3	16
OVARY	Regulation of cell cycle checkpoint →	+0.107	+0.897	<.001	<.001	3	15
PANCREAS	Cell cycle DNA replication initiation →	+0.217	+0.962	<.001	<.001	3	15
PANCREAS	Nuclear cell cycle DNA replication initiation →	+0.217	+0.962	<.001	<.001	3	15
PANCREAS	Mitotic DNA replication initiation →	+0.217	+0.962	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,423 associations by consensus.

Mitotic DNA replication by HIRIP3 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →