HIRIP3

Across TCGA cell cohorts, HIRIP3 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible HIRIP3-associated genes across cancer lineages are IL2, NLRP8, and OR10R2. Each is linked with HIRIP3 in more than 1 cancer types. Because this analysis shows association rather than direction, both HIRIP3-to-partner and partner-to-HIRIP3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IL2 grouped by HIRIP3-low versus HIRIP3-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HIRIP3→partner) and Y-score (partner→HIRIP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	IL2 →	+0.032	+5.196	<.001	.005	3	1
OVARY	NLRP8 →	+0.006	+5.196	<.001	.005	3	1
BLOOD_Leukemia	OR10R2 →	+1.283	+4.551	.006	.004	3	1
BREAST	UBTFL1 →	+0.026	+5.169	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

IL2 by HIRIP3 expression — OVARY

Explore this box plot interactively →