HIPK3

Across TCGA patient cohorts, HIPK3 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,407 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible HIPK3-associated proteins across cancer lineages are SORBS1, OXA1L, and EHD2_S438. Each is linked with HIPK3 in more than 5 cancer types. Because this analysis shows association rather than direction, both HIPK3-to-partner and partner-to-HIPK3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HIPK3 versus SORBS1 in BRCA, with a Pearson correlation of 0.36.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HIPK3→partner) and Y-score (partner→HIPK3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SORBS1 →	+0.741	+0.728	<.001	<.001	3	6
PDAC	OXA1L →	-0.407	-0.256	.001	<.001	3	6
PDAC	EHD2_S438 →	+0.849	+0.348	<.001	<.001	3	5
BRCA	SSC5D →	+0.795	+0.597	<.001	.001	3	5
LUAD	TLN1_S2040 →	+0.593	+0.368	<.001	<.001	3	5
BRCA	PPM1F →	+0.238	+0.635	.002	.003	2	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,407 associations by consensus.

HIPK3 vs SORBS1 — BRCA

Explore this scatter interactively →