HIPK3

Across TCGA cell cohorts, HIPK3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,992 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible HIPK3-associated GO terms across cancer lineages are Endosomal transport, Golgi vesicle transport, and Macroautophagy. Each is linked with HIPK3 in more than 14 cancer types. Because this analysis shows association rather than direction, both HIPK3-to-partner and partner-to-HIPK3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endosomal transport grouped by HIPK3-low versus HIPK3-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HIPK3→partner) and Y-score (partner→HIPK3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Endosomal transport →	+0.083	+1.167	<.001	<.001	3	15
OVARY	Golgi vesicle transport →	+0.066	+1.050	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Macroautophagy →	+0.081	+1.013	<.001	<.001	3	14
KIDNEY	Peptidyl-serine phosphorylation →	+0.089	+0.589	<.001	.004	3	14
KIDNEY	Peptidyl-serine modification →	+0.086	+0.580	.001	.004	3	14
UPPER_AERODIGESTIVE_TRACT	mRNA transcription →	+0.117	+0.850	<.001	.007	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,992 associations by consensus.

Endosomal transport by HIPK3 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →