HINT2P1

Across TCGA pan-cancer cohorts, HINT2P1 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of HINT2P1’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where HINT2P1 RNA is repressed in tumor relative to normal tissue. In most cancer types HINT2P1 is over-expressed in tumor, although a few such as BRCA show the opposite, repressed pattern.

BRCA and HNSC are the cancer types where HINT2P1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in HINT2P1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	All	III,IV	−0.034	.010	2	view →
HNSC	All	III,IV	+0.047	.024	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

HINT2P1–BRCA

Open the BRCA breakdown →