HILPDA

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, HILPDA RNA expression is significantly associated with the protein abundance of many other proteins, with 16,867 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible HILPDA-associated proteins across cancer lineages are SLC2A1, ERO1A, and NARF. Each is linked with HILPDA in more than 6 cancer types. Because this analysis shows association rather than direction, both HILPDA-to-partner and partner-to-HILPDA results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HILPDA versus SLC2A1 in HNSC, with a Pearson correlation of 0.42.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HILPDA→partner) and Y-score (partner→HILPDA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCSLC2A1 →+0.880+1.031<.001<.00137
HNSCERO1A →+0.627+1.189<.001<.00137
GBMNARF →+0.481+1.491<.001<.00136
GBMPFKFB4 →+0.375+1.157<.001<.00136
HNSCRFX5 →-0.444-1.065<.001<.00136
BRCASCLY →-0.428-0.788<.001<.00136
Each partner links to its Q-omics profile. Showing the 6 strongest of 16,867 associations by consensus.

HILPDA vs SLC2A1 — HNSC

Per-sample scatter of HILPDA vs SLC2A1 in HNSC (Pearson r = 0.42).

Explore this scatter interactively →

Exploration