HILPDA

Across TCGA patient cohorts, HILPDA mutation is significantly associated with the total protein of many other genes, with 1 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible HILPDA-associated genes across cancer lineages are Ku80. Each is linked with HILPDA in more than 1 cancer types. Because this analysis shows association rather than direction, both HILPDA-to-partner and partner-to-HILPDA results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Ku80 grouped by HILPDA-low versus HILPDA-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HILPDA→partner) and Y-score (partner→HILPDA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Ku80 →	+0.401	+2.820	.005	.035	3	1

Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

Ku80 by HILPDA expression — UCEC

Explore this box plot interactively →