HIGD2B

Across TCGA patient cohorts, HIGD2B RNA expression is significantly associated with the RNA expression of many other genes, with 6,580 significant associations in total. TGCT shows the largest number of these associations.

The most reproducible HIGD2B-associated genes across cancer lineages are C9orf43, DCST1-AS1, and COA6-AS1. Each is linked with HIGD2B in more than 19 cancer types. Because this analysis shows association rather than direction, both HIGD2B-to-partner and partner-to-HIGD2B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HIGD2B versus C9orf43 in TGCT, with a Pearson correlation of 0.71.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HIGD2B→partner) and Y-score (partner→HIGD2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
TGCT	C9orf43 →	+0.632	+0.232	<.001	<.001	3	20
TGCT	DCST1-AS1 →	+0.716	+0.159	<.001	<.001	3	19
KIRP	COA6-AS1 →	+0.696	+0.106	<.001	<.001	3	18
GBM	YTHDF3-AS1 →	+0.532	+0.105	<.001	.001	3	18
TGCT	SRP14-AS1 →	+0.595	+0.201	<.001	<.001	3	17
KIRP	RPL9P29 →	+0.640	+0.081	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,580 associations by consensus.

HIGD2B vs C9orf43 — TGCT

Explore this scatter interactively →