HIGD2A

Across TCGA patient cohorts, HIGD2A RNA expression is significantly associated with the protein abundance of many other proteins, with 7,793 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible HIGD2A-associated proteins across cancer lineages are NPM1, DIAPH1, and GEMIN5. Each is linked with HIGD2A in more than 5 cancer types. Because this analysis shows association rather than direction, both HIGD2A-to-partner and partner-to-HIGD2A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HIGD2A versus NPM1 in OV, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HIGD2A→partner) and Y-score (partner→HIGD2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	NPM1 →	+0.490	+0.670	<.001	<.001	3	6
CCRCC	DIAPH1 →	+0.236	+0.347	<.001	<.001	3	5
LSCC	GEMIN5 →	+0.257	+0.384	<.001	<.001	3	5
OV	HNRNPAB →	+0.379	+0.418	<.001	.003	3	5
HNSC	KDM3B →	+0.302	+0.954	<.001	<.001	3	5
OV	LARP1 →	+0.263	+0.651	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,793 associations by consensus.

HIGD2A vs NPM1 — OV

Explore this scatter interactively →