Across TCGA cell cohorts, HIGD1C RNA expression is significantly associated with the mutation status of many other genes, with 125 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible HIGD1C-associated genes across cancer lineages are COL4A5, SLC4A3, and MYH13. Each is linked with HIGD1C in more than 1 cancer types. Because this analysis shows association rather than direction, both HIGD1C-to-partner and partner-to-HIGD1C results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HIGD1C→partner) and Y-score (partner→HIGD1C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	COL4A5 →	+5.000	+0.126	.005	<.001	3	2
BREAST	SLC4A3 →	+3.672	+0.145	.006	<.001	3	2
BREAST	MYH13 →	+3.672	+0.152	.006	<.001	3	2
BLOOD_Leukemia	NSD1 →	+2.786	+0.038	.009	.001	3	2
BLOOD_Leukemia	ATP11C →	+3.786	+0.054	.002	<.001	3	2
UPPER_AERODIGESTIVE_TRACT	NBEAL1 →	+4.321	+0.060	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 125 associations by consensus.

Exploration

HIGD1C survival (RNA) · tumor vs normal (RNA) · all HIGD1C data types