Across TCGA patient cohorts, HIGD1AP8 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,706 significant associations in total. STAD shows the largest number of these associations.

The most reproducible HIGD1AP8-associated GO terms across cancer lineages are Cellular response to UV-C, Obsolete histone methylation, and Positive regulation of peptidyl-lysine acetylation. Each is linked with HIGD1AP8 in more than 7 cancer types. Because this analysis shows association rather than direction, both HIGD1AP8-to-partner and partner-to-HIGD1AP8 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HIGD1AP8→partner) and Y-score (partner→HIGD1AP8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	Cellular response to UV-C →	+0.028	+0.085	<.001	.001	3	8
LAML	Obsolete histone methylation →	+0.043	+0.570	<.001	<.001	3	6
LAML	Positive regulation of peptidyl-lysine acetylation →	+0.063	+0.755	<.001	<.001	3	6
LAML	Positive regulation of centriole elongation →	+0.065	+0.802	<.001	<.001	3	6
ESCA	Positive regulation of DNA methylation-dependent heterochromatin formation →	+0.045	+0.165	.001	.007	1	7
UVM	Positive regulation of neuron projection development →	+0.029	+0.049	.005	.007	2	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,706 associations by consensus.

Exploration

HIGD1AP8 survival (RNA) · tumor vs normal (RNA) · all HIGD1AP8 data types