HIGD1AP6

Across TCGA patient cohorts, HIGD1AP6 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,593 significant associations in total. STAD shows the largest number of these associations.

The most reproducible HIGD1AP6-associated GO terms across cancer lineages are mRNA modification, Alternative mRNA splicing, via spliceosome, and Nuclear-transcribed mRNA catabolic process. Each is linked with HIGD1AP6 in more than 17 cancer types. Because this analysis shows association rather than direction, both HIGD1AP6-to-partner and partner-to-HIGD1AP6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, mRNA modification grouped by HIGD1AP6-low versus HIGD1AP6-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HIGD1AP6→partner) and Y-score (partner→HIGD1AP6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	mRNA modification →	+0.058	+0.306	<.001	<.001	3	18
ESCA	Alternative mRNA splicing, via spliceosome →	+0.064	+0.493	<.001	<.001	3	18
STAD	Nuclear-transcribed mRNA catabolic process →	+0.063	+0.285	<.001	<.001	3	17
ESCA	Regulation of mRNA processing →	+0.065	+0.436	<.001	<.001	3	16
STAD	Positive regulation of chromosome organization →	+0.068	+0.318	<.001	<.001	3	16
STAD	Nucleobase-containing compound transport →	+0.061	+0.355	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,593 associations by consensus.

mRNA modification by HIGD1AP6 expression — STAD

Explore this box plot interactively →