HIGD1AP5

Across TCGA patient cohorts, HIGD1AP5 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,949 significant associations in total. STAD shows the largest number of these associations.

The most reproducible HIGD1AP5-associated GO terms across cancer lineages are RNA modification, Cytochrome complex assembly, and Regulation of protein localization to membrane. Each is linked with HIGD1AP5 in more than 6 cancer types. Because this analysis shows association rather than direction, both HIGD1AP5-to-partner and partner-to-HIGD1AP5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA modification grouped by HIGD1AP5-low versus HIGD1AP5-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HIGD1AP5→partner) and Y-score (partner→HIGD1AP5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	RNA modification →	+0.093	+0.146	<.001	.001	3	7
ESCA	Cytochrome complex assembly →	+0.083	+0.102	<.001	.001	3	7
ESCA	Regulation of protein localization to membrane →	+0.080	+0.095	<.001	.002	3	6
ESCA	Amino acid metabolic process →	+0.062	+0.096	<.001	.002	3	6
ESCA	Protein localization to mitochondrion →	+0.090	+0.184	<.001	<.001	2	7
ESCA	Response to UV →	+0.094	+0.103	<.001	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,949 associations by consensus.

RNA modification by HIGD1AP5 expression — ESCA

Explore this box plot interactively →