Q-omics provides the consensus-scored HIGD1AP5 profile across patient tissues and cancer cell-line models. HIGD1AP5 expression is associated with patient survival in 15 of 34 cancer types, with the highest sampling consensus in STAD. Additionally, HIGD1AP5 RNA expression shows 5,949 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight STAD as cancer lineages where HIGD1AP5 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

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Survival associations

This table summarizes HIGD1AP5 survival associations across molecular data types. HIGD1AP5 RNA expression shows survival associations in the most cancer types (15). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

HIGD1AP5 data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	15	STAD (66)	view →

This table ranks reproducible HIGD1AP5 RNA expression–survival associations across cancer types. High HIGD1AP5 expression shows unfavorable associations in STAD, ACC, KIRC, MESO, BRCA and LAML. The STAD Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .007). Together, the overview and detailed table identify STAD as the clearest survival context for HIGD1AP5 RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
STAD	OS	Tertile	II,III,IV	0.555	0.701	.007	66	view →
ACC	DFS	Tertile	All	0.048	0.667	<.001	54	view →
KIRC	DFS	Tertile	IV	0.205	0.603	.001	54	view →
MESO	OS	Tertile	II,III,IV	0.121	0.571	.004	36	view →
BRCA	DFS	Tertile	All	0.140	1.000	.001	36	view →
LAML	DFS	Tertile	All	0.206	0.584	.003	36	view →

Pink = unfavorable, green = favorable. all 15 lineages →

HIGD1AP5-STAD (OS)

Kaplan–Meier survival curve for HIGD1AP5 RNA expression in STAD: high vs low expression groups.

Explore this curve interactively →

Cross-omics associations

This table shows molecular features associated with HIGD1AP5 in patient tissues and cancer cell lines. In patient samples, HIGD1AP5 shows the broadest associations at the RNA and protein expression levels, with STAD recurring as the lineage with the largest associated feature set.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
Function (RNA)	5,949	STAD (5563)	view →
RNA	3,948	COAD (1852)	view →