HIGD1AP4

Across TCGA patient cohorts, HIGD1AP4 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,942 significant associations in total. STAD shows the largest number of these associations.

The most reproducible HIGD1AP4-associated GO terms across cancer lineages are Pyrimidine nucleoside triphosphate biosynthetic process, Pigment granule localization, and Pyrimidine nucleoside triphosphate metabolic process. Each is linked with HIGD1AP4 in more than 7 cancer types. Because this analysis shows association rather than direction, both HIGD1AP4-to-partner and partner-to-HIGD1AP4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Pyrimidine nucleoside triphosphate biosynthetic process grouped by HIGD1AP4-low versus HIGD1AP4-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HIGD1AP4→partner) and Y-score (partner→HIGD1AP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Pyrimidine nucleoside triphosphate biosynthetic process →	+0.080	+0.063	<.001	<.001	3	8
STAD	Pigment granule localization →	+0.069	+0.054	<.001	<.001	3	7
STAD	Pyrimidine nucleoside triphosphate metabolic process →	+0.084	+0.052	<.001	<.001	3	7
STAD	Pyrimidine ribonucleoside triphosphate biosynthetic process →	+0.067	+0.057	<.001	<.001	3	7
STAD	Ribosomal small subunit biogenesis →	+0.128	+0.054	<.001	<.001	3	6
STAD	Regulation of ATP-dependent activity →	+0.075	+0.046	<.001	.002	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,942 associations by consensus.

Pyrimidine nucleoside triphosphate biosynthetic process by HIGD1AP4 expression — STAD

Explore this box plot interactively →