HIGD1AP3

Across TCGA patient cohorts, HIGD1AP3 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,770 significant associations in total. STAD shows the largest number of these associations.

The most reproducible HIGD1AP3-associated GO terms across cancer lineages are Respiratory electron transport chain, Mitochondrial translation, and Amino acid activation. Each is linked with HIGD1AP3 in more than 9 cancer types. Because this analysis shows association rather than direction, both HIGD1AP3-to-partner and partner-to-HIGD1AP3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Respiratory electron transport chain grouped by HIGD1AP3-low versus HIGD1AP3-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HIGD1AP3→partner) and Y-score (partner→HIGD1AP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Respiratory electron transport chain →	+0.053	+0.114	<.001	<.001	3	9
LUSC	Mitochondrial translation →	+0.068	+0.040	<.001	.006	1	10
UCEC	Amino acid activation →	+0.044	+0.072	<.001	<.001	3	8
UCEC	Peptide transport →	+0.023	+0.055	<.001	<.001	3	7
UCEC	Cytoplasmic translation →	+0.055	+0.042	<.001	<.001	3	7
UCEC	Electron transport chain →	+0.053	+0.047	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,770 associations by consensus.

Respiratory electron transport chain by HIGD1AP3 expression — STAD

Explore this box plot interactively →