HIGD1AP2

Across TCGA patient cohorts, HIGD1AP2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,497 significant associations in total. STAD shows the largest number of these associations.

The most reproducible HIGD1AP2-associated GO terms across cancer lineages are Cellular response to light stimulus, Nucleoside phosphate biosynthetic process, and Cytokinesis. Each is linked with HIGD1AP2 in more than 7 cancer types. Because this analysis shows association rather than direction, both HIGD1AP2-to-partner and partner-to-HIGD1AP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cellular response to light stimulus grouped by HIGD1AP2-low versus HIGD1AP2-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HIGD1AP2→partner) and Y-score (partner→HIGD1AP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Cellular response to light stimulus →	+0.097	+0.222	<.001	.002	3	8
STAD	Nucleoside phosphate biosynthetic process →	+0.098	+0.099	<.001	<.001	3	7
ESCA	Cytokinesis →	+0.118	+0.195	<.001	.001	3	7
ESCA	Positive regulation of DNA metabolic process →	+0.117	+0.217	<.001	.002	3	7
ESCA	Establishment of protein localization to membrane →	+0.110	+0.233	<.001	.001	3	7
ESCA	Negative regulation of cellular catabolic process →	+0.107	+0.164	<.001	.002	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,497 associations by consensus.

Cellular response to light stimulus by HIGD1AP2 expression — ESCA

Explore this box plot interactively →