Q-omics provides the consensus-scored HIGD1AP2 profile across patient tissues and cancer cell-line models. HIGD1AP2 expression is associated with patient survival in 9 of 34 cancer types, with the highest sampling consensus in KIRC. Additionally, HIGD1AP2 RNA expression shows 8,010 significant gene co-expression associations, with the highest sampling consensus in LIHC. Together, these results highlight KIRC, and LIHC as cancer lineages where HIGD1AP2 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

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Survival associations

This table summarizes HIGD1AP2 survival associations across molecular data types. HIGD1AP2 RNA expression shows survival associations in the most cancer types (9). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

HIGD1AP2 data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	9	KIRC (126)	view →

This table ranks reproducible HIGD1AP2 RNA expression–survival associations across cancer types. High HIGD1AP2 expression shows unfavorable associations in KIRC, LIHC, HNSC, ESCA, TGCT and ACC. The KIRC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify KIRC as the clearest survival context for HIGD1AP2 RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Tertile	II,III,IV	0.093	0.810	<.001	126	view →
LIHC	OS	Tertile	III,IV	0.093	0.615	<.001	54	view →
HNSC	OS	Tertile	II,III,IV	0.170	0.601	.018	45	view →
ESCA	OS	Tertile	IV	0.095	0.512	.008	36	view →
TGCT	OS	Tertile	All	0.817	0.968	.027	18	view →
ACC	OS	Tertile	II,III,IV	0.268	0.766	.021	18	view →

Pink = unfavorable, green = favorable. all 9 lineages →

HIGD1AP2-KIRC (OS)

Kaplan–Meier survival curve for HIGD1AP2 RNA expression in KIRC: high vs low expression groups.

Explore this curve interactively →

Cross-omics associations

This table shows molecular features associated with HIGD1AP2 in patient tissues and cancer cell lines. In patient samples, HIGD1AP2 shows the broadest associations at the RNA and protein expression levels, with LIHC recurring as the lineage with the largest associated feature set.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
RNA	8,010	LIHC (2044)	view →
Function (RNA)	5,497	STAD (5322)	view →