HIGD1AP1

Across TCGA patient cohorts, HIGD1AP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,667 significant associations in total. STAD shows the largest number of these associations.

The most reproducible HIGD1AP1-associated GO terms across cancer lineages are Mitochondrial RNA catabolic process, Membrane fission, and COPII-coated vesicle budding. Each is linked with HIGD1AP1 in more than 24 cancer types. Because this analysis shows association rather than direction, both HIGD1AP1-to-partner and partner-to-HIGD1AP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrial RNA catabolic process grouped by HIGD1AP1-low versus HIGD1AP1-high in UCS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HIGD1AP1→partner) and Y-score (partner→HIGD1AP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCS	Mitochondrial RNA catabolic process →	+0.052	+0.685	<.001	<.001	3	25
STAD	Membrane fission →	+0.050	+0.249	<.001	<.001	3	24
STAD	COPII-coated vesicle budding →	+0.044	+0.299	<.001	<.001	3	22
KICH	Regulation of mitochondrial mRNA stability →	+0.054	+0.509	<.001	<.001	2	23
STAD	tRNA modification →	+0.035	+0.274	<.001	<.001	3	21
ACC	Mitochondrial translational elongation →	+0.063	+0.287	<.001	<.001	3	21

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,667 associations by consensus.

Mitochondrial RNA catabolic process by HIGD1AP1 expression — UCS

Explore this box plot interactively →