HIGD1A

Across TCGA patient cohorts, HIGD1A RNA expression is significantly associated with the protein abundance of many other proteins, with 10,079 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible HIGD1A-associated proteins across cancer lineages are GOLGA4, TMF1, and TOM1L2. Each is linked with HIGD1A in more than 4 cancer types. Because this analysis shows association rather than direction, both HIGD1A-to-partner and partner-to-HIGD1A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HIGD1A versus GOLGA4 in COAD, with a Pearson correlation of 0.45.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HIGD1A→partner) and Y-score (partner→HIGD1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	GOLGA4 →	+0.237	+0.781	<.001	<.001	3	5
BRCA	TMF1 →	+0.335	+0.828	<.001	<.001	3	4
BRCA	TOM1L2 →	+0.374	+0.882	<.001	<.001	3	4
BRCA	SSH3 →	+0.436	+0.714	.001	<.001	3	3
COAD	SYTL1 →	+0.604	+0.490	.001	<.001	3	3
BRCA	SYTL2 →	+0.647	+0.582	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,079 associations by consensus.

HIGD1A vs GOLGA4 — COAD

Explore this scatter interactively →