HIF1AN

Across TCGA patient cohorts, HIF1AN protein abundance is significantly associated with the RNA expression of many other genes, with 4,311 significant associations in total. OV shows the largest number of these associations.

The most reproducible HIF1AN-associated genes across cancer lineages are MMS19, ACTR1A, and PI4K2A. Each is linked with HIF1AN in more than 4 cancer types. Because this analysis shows association rather than direction, both HIF1AN-to-partner and partner-to-HIF1AN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HIF1AN versus MMS19 in OV, with a Pearson correlation of 0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HIF1AN→partner) and Y-score (partner→HIF1AN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	MMS19 →	+0.465	+0.295	.001	.001	3	5
LUAD	ACTR1A →	+0.339	+0.149	<.001	<.001	3	4
LSCC	PI4K2A →	+0.508	+0.228	<.001	<.001	3	4
OV	TWNK →	+0.623	+0.273	.001	.002	3	4
OV	LZTS2 →	+0.587	+0.384	.002	<.001	3	4
OV	FBXW4 →	+0.621	+0.386	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,311 associations by consensus.

HIF1AN vs MMS19 — OV

Explore this scatter interactively →