HID1-AS1

Across TCGA pan-cancer cohorts, HID1-AS1 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated HID1-AS1 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher HID1-AS1 RNA is associated with better overall survival. In most high-consensus cancer types, elevated HID1-AS1 expression acts as an unfavorable survival marker, although some lineages such as KIRC and HNSC show a favorable association.

KIRC, MESO, and HNSC are the cancer types where HID1-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Median	All	0.714	0.556	<.001	85	view →
MESO	OS	Quartile	All	0.242	0.548	<.001	59	view →
HNSC	DFS	Quartile	III,IV	0.437	0.264	.005	26	view →
KICH	OS	Median	III,IV	1.000	0.792	.017	25	view →
BRCA	DFS	Median	All	0.443	0.594	.001	22	view →
THCA	DFS	Median	All	0.891	0.773	.001	21	view →
UVM	OS	Tertile	II,III,IV	0.699	0.915	.028	13	view →
LGG	OS	Median	All	0.334	0.550	.001	12	view →
UCEC	OS	Quartile	All	0.902	0.953	.024	10	view →
ESCA	DFS	Tertile	II,III,IV	0.339	1.000	.022	9	view →
SKCM	DFS	Tertile	II,III,IV	0.595	0.753	.027	7	view →
BLCA	OS	Tertile	II,III,IV	0.652	0.542	.031	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

HID1-AS1–KIRC (OS)

Open the KIRC breakdown →