HHATL-AS1

Across TCGA pan-cancer cohorts, HHATL-AS1 RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated HHATL-AS1 data layer.

The strongest signal is observed in mesothelioma (MESO), where higher HHATL-AS1 RNA is associated with better overall survival. In most high-consensus cancer types, elevated HHATL-AS1 expression acts as an unfavorable survival marker, although some lineages such as MESO and KIRP show a favorable association.

MESO, KIRP, and CESC are the cancer types where HHATL-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	OS	Median	III,IV	0.522	0.276	<.001	75	view →
KIRP	DFS	Median	All	0.973	0.793	.006	43	view →
CESC	DFS	Tertile	II,III,IV	0.877	0.441	.002	40	view →
CHOL	OS	Tertile	IV	0.024	0.732	.014	36	view →
LUSC	OS	Tertile	IV	0.001	0.673	.014	36	view →
UCEC	OS	Quartile	All	0.970	0.896	.010	36	view →
UVM	OS	Tertile	II,III,IV	0.758	0.267	.005	33	view →
SKCM	OS	Quartile	III,IV	0.944	0.695	.005	30	view →
PAAD	OS	Median	All	0.656	0.328	.003	22	view →
READ	DFS	Tertile	IV	0.112	0.811	.008	18	view →
LAML	DFS	Tertile	All	0.476	0.647	.021	12	view →
UCS	DFS	Tertile	II,III,IV	0.719	0.346	.014	8	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 18 lineages.

HHATL-AS1–MESO (OS)

Open the MESO breakdown →