HGH1

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, HGH1 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,251 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible HGH1-associated proteins across cancer lineages are SCRIB, C8orf33, and HSF1. Each is linked with HGH1 in more than 7 cancer types. Because this analysis shows association rather than direction, both HGH1-to-partner and partner-to-HGH1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HGH1 versus SCRIB in LSCC, with a Pearson correlation of 0.80.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HGH1→partner) and Y-score (partner→HGH1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCSCRIB →+0.382+0.684<.001<.00138
BRCAC8orf33 →+0.443+0.619<.001<.00137
OVHSF1 →+0.767+0.863<.001.00136
OVPYCR3 →+0.402+0.641<.001<.00136
BRCANUDCD1 →+0.357+0.483<.001.00135
LSCCPRKDC →+0.312+0.642<.001<.00135
Each partner links to its Q-omics profile. Showing the 6 strongest of 14,251 associations by consensus.

HGH1 vs SCRIB — LSCC

Per-sample scatter of HGH1 vs SCRIB in LSCC (Pearson r = 0.80).

Explore this scatter interactively →

Exploration