HGH1

Across TCGA pan-cancer cohorts, HGH1 RNA differs between tumor and matched normal tissue in 16 of 18 cancer types tested, making tumor–normal expression one of HGH1’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where HGH1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types HGH1 is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.

COAD, HNSC, and KIRC are the cancer types where HGH1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in HGH1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Male	IV	+1.764	<.001	12	view →
HNSC	All	IV	+0.952	<.001	12	view →
KIRC	All	IV	+0.639	<.001	12	view →
BLCA	Female	III,IV	+1.402	<.001	11	view →
STAD	Male	III,IV	+2.096	<.001	10	view →
LIHC	Male	II,III,IV	+1.627	<.001	9	view →
LUAD	Female	III,IV	+1.275	<.001	9	view →
LUSC	All	III,IV	+1.658	<.001	8	view →
KIRP	Female	II,III,IV	+0.690	<.001	8	view →
BRCA	All	III,IV	+1.271	<.001	6	view →
UCEC	All	III,IV	+1.221	<.001	6	view →
CHOL	Female	All	+1.856	<.001	3	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 16 lineages.

HGH1–COAD

Open the COAD breakdown →