HGH1

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, HGH1 protein abundance is significantly associated with the RNA expression of many other genes, with 8,729 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible HGH1-associated genes across cancer lineages are GFUS, CHRAC1, and MED30. Each is linked with HGH1 in more than 6 cancer types. Because this analysis shows association rather than direction, both HGH1-to-partner and partner-to-HGH1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HGH1 versus GFUS in OV, with a Pearson correlation of 0.47.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HGH1→partner) and Y-score (partner→HGH1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVGFUS →+0.798+0.375.001<.00137
HNSCCHRAC1 →+0.785+0.225.001<.00136
BRCAMED30 →+0.502+0.245<.001<.00136
COADTMEM70 →+0.559+0.207<.001<.00136
BRCAPTK2 →+0.605+0.405<.001<.00136
BRCARRS1 →+0.655+0.328<.001<.00136
Each partner links to its Q-omics profile. Showing the 6 strongest of 8,729 associations by consensus.

HGH1 vs GFUS — OV

Per-sample scatter of HGH1 vs GFUS in OV (Pearson r = 0.47).

Explore this scatter interactively →

Exploration