HGH1

Across TCGA cell cohorts, HGH1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,488 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible HGH1-associated GO terms across cancer lineages are Nucleosome disassembly, P-body assembly, and Protein-DNA complex disassembly. Each is linked with HGH1 in more than 15 cancer types. Because this analysis shows association rather than direction, both HGH1-to-partner and partner-to-HGH1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nucleosome disassembly grouped by HGH1-low versus HGH1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HGH1→partner) and Y-score (partner→HGH1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Nucleosome disassembly →	+0.214	+1.130	<.001	.001	3	16
BONE	P-body assembly →	+0.101	+1.115	.005	.002	3	13
BONE	Protein-DNA complex disassembly →	+0.177	+1.031	<.001	.003	3	13
SKIN	Termination of RNA polymerase III transcription →	+0.121	+0.608	<.001	<.001	3	12
PANCREAS	Maintenance of sister chromatid cohesion →	+0.161	+0.930	<.001	<.001	3	12
PANCREAS	Maintenance of mitotic sister chromatid cohesion →	+0.161	+0.930	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,488 associations by consensus.

Nucleosome disassembly by HGH1 expression — BONE

Explore this box plot interactively →