HGF

Across TCGA patient cohorts, HGF RNA expression is significantly associated with the RNA expression of many other genes, with 18,652 significant associations in total. THYM shows the largest number of these associations.

The most reproducible HGF-associated genes across cancer lineages are ITGA4, AXL, and F2R. Each is linked with HGF in more than 31 cancer types. Because this analysis shows association rather than direction, both HGF-to-partner and partner-to-HGF results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HGF versus ITGA4 in SKCM, with a Pearson correlation of 0.45.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HGF→partner) and Y-score (partner→HGF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	ITGA4 →	+1.760	+0.797	<.001	<.001	3	32
SKCM	AXL →	+1.653	+0.904	<.001	<.001	3	32
THYM	F2R →	+2.507	+0.626	<.001	<.001	3	31
TGCT	FAT4 →	+1.489	+1.580	<.001	<.001	3	31
SKCM	MAN1A1 →	+1.723	+0.878	<.001	<.001	3	30
ACC	F13A1 →	+2.383	+0.987	<.001	<.001	3	30

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,652 associations by consensus.

HGF vs ITGA4 — SKCM

Explore this scatter interactively →