HEY1

Across TCGA cell cohorts, HEY1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,666 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible HEY1-associated GO terms across cancer lineages are Trabecula formation, Aerobic respiration, and Heart trabecula formation. Each is linked with HEY1 in more than 8 cancer types. Because this analysis shows association rather than direction, both HEY1-to-partner and partner-to-HEY1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Trabecula formation grouped by HEY1-low versus HEY1-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HEY1→partner) and Y-score (partner→HEY1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Trabecula formation →	-0.317	-1.640	<.001	<.001	3	9
UPPER_AERODIGESTIVE_TRACT	Aerobic respiration →	+0.052	+0.987	.007	.004	3	8
BLOOD_Leukemia	Heart trabecula formation →	-0.307	-1.422	<.001	<.001	3	8
BLOOD_Lymphoma	Establishment of protein localization to organelle →	+0.063	+0.997	<.001	<.001	3	8
SKIN	Purine ribonucleoside triphosphate metabolic process →	+0.052	+1.547	.009	.004	2	9
STOMACH	Purine nucleoside triphosphate metabolic process →	+0.070	+1.913	.007	.005	2	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,666 associations by consensus.

Trabecula formation by HEY1 expression — STOMACH

Explore this box plot interactively →