HEXIM2

Across TCGA patient cohorts, HEXIM2 protein abundance is significantly associated with the RNA expression of many other genes, with 6,502 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible HEXIM2-associated genes across cancer lineages are KCTD6, NIFK-AS1, and DIS3L. Each is linked with HEXIM2 in more than 2 cancer types. Because this analysis shows association rather than direction, both HEXIM2-to-partner and partner-to-HEXIM2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HEXIM2 versus KCTD6 in BRCA, with a Pearson correlation of 0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HEXIM2→partner) and Y-score (partner→HEXIM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	KCTD6 →	+0.726	+0.494	<.001	<.001	3	3
OV	NIFK-AS1 →	+0.602	+0.654	.001	.008	3	3
HNSC	DIS3L →	+0.548	+0.585	.005	<.001	3	3
GBM	RNF157-AS1 →	+0.364	+0.210	.001	<.001	3	3
COAD	MSH6 →	+0.811	+0.521	<.001	.001	3	2
HNSC	DTNB →	+0.559	+0.407	.009	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,502 associations by consensus.

HEXIM2 vs KCTD6 — BRCA

Explore this scatter interactively →