HERPUD1

Across TCGA patient cohorts, HERPUD1 mutation is significantly associated with the RNA expression of many other genes, with 692 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible HERPUD1-associated genes across cancer lineages are RNU1-139P, HMGB3P8, and LINC01899. Each is linked with HERPUD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both HERPUD1-to-partner and partner-to-HERPUD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU1-139P grouped by HERPUD1-low versus HERPUD1-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HERPUD1→partner) and Y-score (partner→HERPUD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	RNU1-139P →	+0.518	+7.924	<.001	.008	3	2
UCEC	HMGB3P8 →	+0.160	+2.205	.005	.001	3	2
UCEC	LINC01899 →	+0.086	+2.260	.001	.004	3	2
UCEC	DUXAP3 →	+0.165	+2.066	<.001	.008	3	2
BLCA	RPL29P32 →	+0.068	+4.562	<.001	.006	3	2
UCEC	CDRT15P9 →	+0.584	+2.981	.005	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 692 associations by consensus.

RNU1-139P by HERPUD1 expression — LUSC

Explore this box plot interactively →