HERC2P8

Across TCGA patient cohorts, HERC2P8 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,669 significant associations in total. STAD shows the largest number of these associations.

The most reproducible HERC2P8-associated GO terms across cancer lineages are Protein polyubiquitination, Telomere maintenance, and snRNA metabolic process. Each is linked with HERC2P8 in more than 28 cancer types. Because this analysis shows association rather than direction, both HERC2P8-to-partner and partner-to-HERC2P8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein polyubiquitination grouped by HERC2P8-low versus HERC2P8-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HERC2P8→partner) and Y-score (partner→HERC2P8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Protein polyubiquitination →	+0.067	+0.096	<.001	<.001	3	29
STAD	Telomere maintenance →	+0.066	+0.052	<.001	<.001	3	29
STAD	snRNA metabolic process →	+0.057	+0.049	<.001	<.001	3	28
ESCA	Endosomal transport →	+0.059	+0.077	<.001	.001	3	28
STAD	Regulation of organelle assembly →	+0.058	+0.040	<.001	<.001	3	28
ESCA	Cytoskeleton-dependent intracellular transport →	+0.055	+0.090	<.001	<.001	3	28

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,669 associations by consensus.

Protein polyubiquitination by HERC2P8 expression — ESCA

Explore this box plot interactively →